Edinburgh · Lothian · Scotland
Edinburgh Genome Foundry
University of Edinburgh
Fully automated robotic assembly of DNA constructs up to a megabase, host-agnostic across bacterial, yeast, plant and mammalian chassis.
About
The Edinburgh Genome Foundry specialises in the modular, fully automated robotic assembly of DNA constructs. It offers end-to-end design, construction and validation of genetic material for academic and industrial customers, building and modifying DNA up to approximately one megabase pair in length.
The facility is host-agnostic — supporting bacterial, yeast, plant and mammalian cell chassis — and is built for the projects that defeat manual work: long constructs above 5 kilobases, assemblies with large numbers of parts, and combinatorial libraries. It also develops and shares open-source software for DNA design and laboratory automation.
Focus areas
- Stem cell engineering
- Vaccine development
- Gene therapy & viral vectors
- Living biosensors
- Cell phenotyping
Notable work
CyanoSource
Generated thousands of cyanobacterial knock-out mutants as a community resource.
Open-source tooling
The CUBA web suite of 20+ design tools and the Dioscuri package for driving Tecan robots.
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