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Norwich · East of England · England

Earlham Biofoundry

Earlham Institute

A National Bioscience Research Infrastructure supported by BBSRC, with automation capabilities for plant and microbial systems.

An Opentrons Flex liquid handler at the Earlham Biofoundry.
© Earlham Institute
A BioLector microbioreactor at the Earlham Biofoundry.
© Earlham Institute

About

The Earlham Biofoundry combines laboratory automation with expertise in large-scale experimentation and synthetic biology, enabling a wide range of molecular and microbiological workflows.

With a focus on plant and microbial applications, the Earlham Biofoundry has developed highly optimised processes for protein–protein interaction studies, DNA regulatory element characterisation, bacterial transformation, and high-throughput microfermentation.

The Earlham Biofoundry also provides training in laboratory automation through practical training sessions, laboratory placements, training courses, and collaborative projects.

Focus areas

  • Synthetic DNA construct production
  • Genetic library creation
  • Plant gene editing
  • Bacterial strain optimisation
  • Cell-free protein synthesis

Notable work

Synthetic plant chromosomes (synPACs)

An ARIA-funded project assembling potato regulatory-element libraries.